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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MOS All Species: 15.45
Human Site: S18 Identified Species: 28.33
UniProt: P00540 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P00540 NP_005363.1 346 37820 S18 L R S E F S P S V D A R P C S
Chimpanzee Pan troglodytes XP_528144 346 37828 S18 L R S E F S P S V D A R P C S
Rhesus Macaque Macaca mulatta XP_001087400 305 33010
Dog Lupus familis XP_544088 372 41133 S42 L P S E F S P S V D S R P C S
Cat Felis silvestris
Mouse Mus musculus P00536 390 42872 S68 E L S P S V D S R S C S I P L
Rat Rattus norvegicus P00539 339 37603 V19 P R E L S P T V D S R S C S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P10741 349 38245 R22 L S P S A D L R P C S S P V V
Frog Xenopus laevis P12965 359 39143 S18 L P R D L S P S I D L R P C S
Zebra Danio Brachydanio rerio NP_991143 329 36509 L17 L L P K D F G L E F G A C S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9U1Y5 476 53320 A62 G I S S I D L A D D H F V C G
Sea Urchin Strong. purpuratus XP_789415 418 47752 T32 Y L Q R T K R T I S T E N L L
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001130627 368 40934 G18 S G G G N G G G P G K R L E R
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q2MHE4 390 44263 S24 S K L P L E P S L P N L P C N
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 85.5 78.4 N.A. 65.3 71 N.A. N.A. 62.1 53.7 46.5 N.A. N.A. N.A. 20.1 26.3
Protein Similarity: 100 99.4 86.4 83.5 N.A. 71.7 78.9 N.A. N.A. 72.7 66.5 62.1 N.A. N.A. N.A. 36.1 40.6
P-Site Identity: 100 100 0 86.6 N.A. 13.3 13.3 N.A. N.A. 13.3 60 13.3 N.A. N.A. N.A. 20 0
P-Site Similarity: 100 100 0 93.3 N.A. 13.3 13.3 N.A. N.A. 20 73.3 20 N.A. N.A. N.A. 26.6 13.3
Percent
Protein Identity: N.A. 29.6 N.A. 22.8 N.A. N.A.
Protein Similarity: N.A. 43.2 N.A. 42 N.A. N.A.
P-Site Identity: N.A. 6.6 N.A. 26.6 N.A. N.A.
P-Site Similarity: N.A. 6.6 N.A. 46.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 0 0 8 0 0 16 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 8 8 0 16 47 0 % C
% Asp: 0 0 0 8 8 16 8 0 16 39 0 0 0 0 0 % D
% Glu: 8 0 8 24 0 8 0 0 8 0 0 8 0 8 0 % E
% Phe: 0 0 0 0 24 8 0 0 0 8 0 8 0 0 0 % F
% Gly: 8 8 8 8 0 8 16 8 0 8 8 0 0 0 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % H
% Ile: 0 8 0 0 8 0 0 0 16 0 0 0 8 0 0 % I
% Lys: 0 8 0 8 0 8 0 0 0 0 8 0 0 0 0 % K
% Leu: 47 24 8 8 16 0 16 8 8 0 8 8 8 8 16 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 8 0 0 0 0 0 8 0 8 0 8 % N
% Pro: 8 16 16 16 0 8 39 0 16 8 0 0 47 8 0 % P
% Gln: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 24 8 8 0 0 8 8 8 0 8 39 0 0 8 % R
% Ser: 16 8 39 16 16 31 0 47 0 24 16 24 0 16 47 % S
% Thr: 0 0 0 0 8 0 8 8 0 0 8 0 0 0 0 % T
% Val: 0 0 0 0 0 8 0 8 24 0 0 0 8 8 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _